Anti-Rubella Virus IgG Liquor

Anti-Rubella Virus IgG Liquor is an ELISA based test system intended for the comparative quantitative measurement of IgG class antibodies against Rubella Virus in human serum or plasma samples and in cerebrospinal fluid (CSF). This assay is applicable for the detection of IgG antibody synthesis in the central nervous system. In chronic diseases with CNS involvement, e.g. multiple sclerosis (MS) or Lupus with neurological manifestations, an elevated antibody index of anti-measles virus, anti-rubella virus and / or anti-varicella zoster virus can be detected in the CSF. This MRZ reaction is the most sensitive biochemical method for the detection of the pathological immune process in the CNS when the first clinical symptoms of MS appear. In about 90% of MS patients, an increased antibody index against the MRZ combination can be detected.

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