Anti-SS-A

Anti-SS-A

Anti-SS-A 60 is an ELISA-based, automated, in-vitro test system for the quantitative determination of IgG antibodies against SS-A-60 in human serum or plasma.

This test is useful for the differential diagnosis and monitoring of systemic rheumatic inflammatory autoimmune diseases. SS-A 60 is a component of the human cytoplasmic ribonucleoprotein complex. The proteins SS-A 60 and SS-A-52 bind to smaller RNAs and ribonucleoprotein particles in the cell nucleus and the cytoplasm. Autoantibodies against SS-A 60 are primarily found in cases of Sjögren’s syndrome and lupus erythematosus. SS-A 60 antibodies frequently appear in conjunction with SS-B and SS-A 52 antibodies.