CoAprovel is used to treat high blood pressure, when treatment with irbesartan or hydrochlorothiazide alone did not provide adequate control of your blood pressure.
Aprovel 150 mg
Aprovel belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Aprovel prevents angiotensin-II binding to these receptors, causing the blood vessels to relax and the blood pressure to lower. Aprovel slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.
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Aprovel 150 mg
Aprovel is used in adult patients:
to treat high blood pressure (essential hypertension)
to protect the kidney in patients with high blood pressure, type 2 diabetes, and laboratory evidence of impaired kidney function.
What you need to know before you take Aprovel
Do not take Aprovel
if you are allergic to irbesartan or any other ingredients of this medicine (listed in section 6)
if you are more than three months pregnant. (It is also better to avoid Aprovel in early pregnancy – see pregnancy section)
if you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren
How to take Aprovel
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Method of administration
Aprovel is for oral use. Swallow the tablets with sufficient fluid (e.g., one glass of water). You can take Aprovel with or without food. Try to take your daily dose at about the same time each day. It is important that you continue to take Aprovel until your doctor tells you otherwise.
Patients with high blood pressure
The usual dose is 150 mg once a day. The dose may later be increased to 300 mg (two tablets a day) once daily, depending on blood pressure response.
Patients with high blood pressure and type 2 diabetes with kidney disease
In patients with high blood pressure and type 2 diabetes, 300 mg (two tablets a day) once daily is the preferred maintenance dose for the treatment of associated kidney disease.
The doctor may advise a lower dose, especially when starting treatment in certain patients, such as those on hemodialysis or those over the age of 75 years.
The maximal blood pressure lowering effect should be reached 4-6 weeks after beginning treatment.
Use in children and adolescentsAprovel should not be given to children under 18 years of age. If a child swallows some tablets, contact your doctor immediately.
If you take more Aprovel than you should:
If you accidentally take too many tablets, contact your doctor immediately.
If you forget to take Aprovel:
If you accidentally miss a daily dose, just take the next dose as normal. Do not take a double dose to make up for a forgotten dose.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.