Anti-Phosphatidyl Inositol IgG
Autoantibodies against phosphatidyl inositol, a negatively charged phospholipid, generally appear together with cardiolipin antibodies and antibodies against phosphatidyl serine. However, anti-phosphatidyl inositol has also been detected by itself in patients with antiphospholipid syndrome (APS). In the absence of anti-cardiolipin and anti-phosphatidyl serine, the detection of phosphatidyl inositol is thus indicative of APS. In addition to the antigen, the wells of the ORGENTEC Anti-Phosphatidyl Inositol test are also coated with human beta-2-glycoprotein I as cofactor.